{"product_id":"tribio-bd1063-dihydrochloride-selective-sigma-1-antagonist","title":"BD1063 dihydrochloride, Selective sigma-1 antagonist","description":"\u003cp\u003eBD1063 is potent and selective sigma-1 antagonist (IC50’s: sigma1 = 9nM, sigma2 = 449nM). BD1063 abolished mechanical and thermal hyperalgesia in mice with carrageenan-induced acute inflammation by enhancing the action of endogenous opioid peptides of immune origin in a sigma1 dependent manner. BD1063 potentiated µ-opioid antinociception in mice in a sigma-dependent manner. BD-1063 has been used in animal models to successfully treat compulsive eating and excessive ethanol drinking\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57410866774356,"sku":"ABM146686-1","price":319.0,"currency_code":"GBP","in_stock":true},{"title":"5 MG","offer_id":57410866807124,"sku":"ABM146686-2","price":82.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI4211.png?v=1791103234","url":"https:\/\/www.abmium.com\/products\/tribio-bd1063-dihydrochloride-selective-sigma-1-antagonist","provider":"ABMIUM","version":"1.0","type":"link"}