{"product_id":"tribio-baricitinib-immunosuppressant-jak1-2-inhibitor","title":"Baricitinib, Immunosuppressant; JAK1\/2 inhibitor","description":"\u003cp\u003eBaricitinib, approved by the FDA for two inflammatory disorders, rheumatoid arthritis and alopecia areata, selectively inhibits Janus kinase 1 (IC50 = 5.9 nM) and 2 (5.7 nM), over 3 (0.56 µM). It thereby blocks JAK\/STAT signaling, reducing cytokine release and suppressing the innate and adaptive immune systems. Was recently shown to significantly improve COVID-19 symptoms in a preliminary human trial, presumably through suppression of the cytokine release syndrome (“cytokine storm”) induced by SARS-CoV-2 infection\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57410863759700,"sku":"ABM146675-1","price":163.0,"currency_code":"GBP","in_stock":true},{"title":"5 MG","offer_id":57410863792468,"sku":"ABM146675-2","price":78.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI3893.png?v=1791103227","url":"https:\/\/www.abmium.com\/products\/tribio-baricitinib-immunosuppressant-jak1-2-inhibitor","provider":"ABMIUM","version":"1.0","type":"link"}