{"product_id":"tribio-axitinib-vegfr-kinase-inhibitor","title":"Axitinib, VEGFR kinase inhibitor","description":"\u003cp\u003ePotent inhibitor of VEGFR-2, -3, and -1, IC50 = 0.2, 0.1-0.3, and 1.2 nM respectively displaying minimal activity against a panel of ~100 protein kinases. Inhibits angiogenesis and vascular permeability. Also inhibits BCR-ABL1 (T315I) with high potency, Ki = 149 pM for autophosphorylated ABL1 (T315I). Inhibits proliferation of Ba\/F3 cells expressing BCR-ABL1 (T315I). Clinically useful anticancer agent\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"10 MG","offer_id":57410856878420,"sku":"ABM146656-1","price":78.0,"currency_code":"USD","in_stock":true},{"title":"50 MG","offer_id":57410856911188,"sku":"ABM146656-2","price":216.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI2118-1.png?v=1791103214","url":"https:\/\/www.abmium.com\/products\/tribio-axitinib-vegfr-kinase-inhibitor","provider":"ABMIUM","version":"1.0","type":"link"}