{"product_id":"tribio-ap-18-trpa1-blocker","title":"AP-18, TRPA1 blocker","description":"\u003cp\u003eTRPA1 channel blocker IC50=3.1-4.5 µM in various cell lines. Reduces cinnamaldehyde-induced nociception in vivo and blocks cold- and mustard oil-induced activation of mouse TRPA1 but not capsaicin-induced activation. Does not block TRPV1, V2, V3, V4 or M8 at concentrations up to 50 µM. Blocks TRPA1 pore dilation (IC50=10.3 µM). An important tool for assessing the role of TRPA1 in cell signaling and physiological processes\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"10 MG","offer_id":57410863268180,"sku":"ABM146618-1","price":106.0,"currency_code":"GBP","in_stock":true},{"title":"50 MG","offer_id":57410863300948,"sku":"ABM146618-2","price":425.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI1127-1.png?v=1791103226","url":"https:\/\/www.abmium.com\/products\/tribio-ap-18-trpa1-blocker","provider":"ABMIUM","version":"1.0","type":"link"}