{"product_id":"tribio-a83-01-alk-inhibitor","title":"A83-01, ALK inhibitor","description":"\u003cp\u003ePotent and selective ALK4, 5 and 7 inhibitor. IC50=45, 12 and 7.5 nM respectively. Prevents phosphorylation of Smad2\/3 and growth inhibition induced by TGFβ2. Inhibits differentiation of rat induced pluripotent stem cells and increases clonal expansion efficiency. Together with AMI-5, A83-01 enabled Oct4-induced reprogramming of mouse embryonic fibroblasts. Cell permeable. Active in vivo\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57410857107796,"sku":"ABM146554-1","price":294.0,"currency_code":"GBP","in_stock":true},{"title":"5 MG","offer_id":57410857140564,"sku":"ABM146554-2","price":82.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI1327.png?v=1791103215","url":"https:\/\/www.abmium.com\/products\/tribio-a83-01-alk-inhibitor","provider":"ABMIUM","version":"1.0","type":"link"}