{"product_id":"reed-biotech-zap-70-polyclonal-antibody-ra36319","title":"ZAP-70 Polyclonal Antibody","description":"\u003cp\u003ezeta chain of T cell receptor associated protein kinase 70(ZAP70) Homo sapiens This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57249722728788,"sku":"ABM5040713-1","price":137.0,"currency_code":"USD","in_stock":true},{"title":"100 µL","offer_id":57249722761556,"sku":"ABM5040713-2","price":184.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_046e9620-bb00-4e06-9c9c-75f7d8400f3b.webp?v=1790235542","url":"https:\/\/www.abmium.com\/products\/reed-biotech-zap-70-polyclonal-antibody-ra36319","provider":"ABMIUM","version":"1.0","type":"link"}