{"product_id":"reed-biotech-tcl1-polyclonal-antibody-ra30364","title":"Tcl1 Polyclonal Antibody","description":"\u003cp\u003eT-cell leukemia\/lymphoma 1A(TCL1A) Homo sapiens Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-\/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).[supplied by OMIM, Jul 2010],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57249641070932,"sku":"ABM5034758-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57249641103700,"sku":"ABM5034758-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_7be27a93-f64a-4fbb-92ce-58ef439b4efc.webp?v=1790235331","url":"https:\/\/www.abmium.com\/products\/reed-biotech-tcl1-polyclonal-antibody-ra30364","provider":"ABMIUM","version":"1.0","type":"link"}