{"product_id":"reed-biotech-tab3-polyclonal-antibody-ra35198","title":"TAB3 Polyclonal Antibody","description":"\u003cp\u003eTGF-beta activated kinase 1\/MAP3K7 binding protein 3(TAB3) Homo sapiens The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2\/TAB2, forms a ternary complex with the protein kinase MAP3K7\/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7\/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250301116756,"sku":"ABM5039592-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250301149524,"sku":"ABM5039592-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_2dc1018c-7364-4ba6-82e8-6a36a32fb36a.webp?v=1790235306","url":"https:\/\/www.abmium.com\/products\/reed-biotech-tab3-polyclonal-antibody-ra35198","provider":"ABMIUM","version":"1.0","type":"link"}