{"product_id":"reed-biotech-smad7-polyclonal-antibody-ra21252","title":"SMAD7 Polyclonal Antibody","description":"\u003cp\u003eSMAD family member 7(SMAD7) Homo sapiens The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57248475545940,"sku":"ABM5025646-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57248475578708,"sku":"ABM5025646-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_c6c0b163-7303-4362-870b-3c6c1c5f6adb.webp?v=1790235203","url":"https:\/\/www.abmium.com\/products\/reed-biotech-smad7-polyclonal-antibody-ra21252","provider":"ABMIUM","version":"1.0","type":"link"}