{"product_id":"reed-biotech-sck-polyclonal-antibody-ra29678","title":"Sck Polyclonal Antibody","description":"\u003cp\u003edomain:The PID domain mediates binding to the TrkA receptor.,function:Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.,miscellaneous:PubMed:15057824 has shown that SHC2 is poorly phosphorylated by the Trk receptors, in opposite to PubMed:12006576.,PTM:Phosphorylated on tyrosines by the Trk receptors.,similarity:Contains 1 PID domain.,similarity:Contains 1 SH2 domain.,subunit:Interacts with the Trk receptors in a phosphotyrosine-dependent manner and MEGF12. Once activated, binds to GRB2.,tissue specificity:Expressed in brain. Expressed at high level in the hypothalamus and at low level in the caudate nucleus.,\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57251061694804,"sku":"ABM5034072-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57251061727572,"sku":"ABM5034072-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_b9731678-7e69-4ade-bfb1-019adf85603f.webp?v=1790235145","url":"https:\/\/www.abmium.com\/products\/reed-biotech-sck-polyclonal-antibody-ra29678","provider":"ABMIUM","version":"1.0","type":"link"}