{"product_id":"reed-biotech-rpgf4-polyclonal-antibody-ra34578","title":"RPGF4 Polyclonal Antibody","description":"\u003cp\u003edomain:The DEP domain is involved in membrane localization independent from regulation by cAMP.,domain:The N-terminal nucleotide phosphate binding region cAMP 1 has a much lower affinity for cAMP as compared to cAMP 2.,function:Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2.,similarity:Contains 1 DEP domain.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 Ras-GEF domain.,similarity:Contains 2 cyclic nucleotide-binding domains.,subunit:Interacts with RIMS1 and RIMS2. Probably part of a complex with RIMS2 and GTP-activated RAB3A.,tissue specificity:Predominantly expressed in brain and adrenal gland. Isoform 2 is expressed in liver. Isoform 1 is expressed in liver at very low levels.,\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250250064212,"sku":"ABM5038972-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250250096980,"sku":"ABM5038972-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_6da503ca-4f4b-4b38-8c50-07937df16bc5.webp?v=1790235094","url":"https:\/\/www.abmium.com\/products\/reed-biotech-rpgf4-polyclonal-antibody-ra34578","provider":"ABMIUM","version":"1.0","type":"link"}