{"product_id":"reed-biotech-phc3-polyclonal-antibody-ra34080","title":"PHC3 Polyclonal Antibody","description":"\u003cp\u003efunction:Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FCS-type zinc finger.,similarity:Contains 1 SAM (sterile alpha motif) domain.,subunit:Component of chromatin-associated class II polycomb repressive complex 1 (PRC1\/hPRC-H) at least composed of PCGF2\/RNF110, BMI1\/PCGF4, CBX2\/M33, CBX4\/PC2, CBX8\/PC3, PHC1, PHC2, PHC3, SCMH1, RING1 and RNF2\/RING2.,\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57251071033684,"sku":"ABM5038474-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57251071066452,"sku":"ABM5038474-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_cc1ecd2a-f883-4e41-a658-e4d2c3f13021.webp?v=1790234881","url":"https:\/\/www.abmium.com\/products\/reed-biotech-phc3-polyclonal-antibody-ra34080","provider":"ABMIUM","version":"1.0","type":"link"}