{"product_id":"reed-biotech-mrp2-polyclonal-antibody-ra21158","title":"MRP2 Polyclonal Antibody","description":"\u003cp\u003eATP binding cassette subfamily C member 2(ABCC2) Homo sapiens The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR\/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57248252690772,"sku":"ABM5025552-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57248252723540,"sku":"ABM5025552-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_7709da99-3c71-41d6-891c-d0696cca79bf.webp?v=1790234529","url":"https:\/\/www.abmium.com\/products\/reed-biotech-mrp2-polyclonal-antibody-ra21158","provider":"ABMIUM","version":"1.0","type":"link"}