{"product_id":"reed-biotech-mc1-r-polyclonal-antibody-ra27072","title":"MC1-R Polyclonal Antibody","description":"\u003cp\u003emelanocortin 1 receptor(MC1R) Homo sapiens This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in de\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57251026075988,"sku":"ABM5031466-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57251026108756,"sku":"ABM5031466-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/products\/reed-biotech-mc1-r-polyclonal-antibody-ra27072","provider":"ABMIUM","version":"1.0","type":"link"}