{"product_id":"reed-biotech-kdm3b-polyclonal-antibody-ra32936","title":"KDM3B Polyclonal Antibody","description":"\u003cp\u003ecofactor:Binds 1 Fe(2+) ion per subunit.,domain:Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.,function:Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.,miscellaneous:Its gene is located in the 5q region of the genome which is deleted in del(5q) interstitial deletion, a frequent deletion found in myeloid leukemias and myelodysplasias, suggesting that it may be a good candidate for the del(5q) tumor suppressor gene.,similarity:Belongs to the JHDM2 histone demethylase family.,similarity:Contains 1 JmjC domain.,tissue specificity:Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver.,\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250007286100,"sku":"ABM5037330-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250007318868,"sku":"ABM5037330-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/products\/reed-biotech-kdm3b-polyclonal-antibody-ra32936","provider":"ABMIUM","version":"1.0","type":"link"}