{"product_id":"reed-biotech-kcnq2-3-4-5-phospho-thr217-246-223-251-polyclonal-antibody-ra26618","title":"KCNQ2\/3\/4\/5 (phospho Thr217\/246\/223\/251) Polyclonal Antibody","description":"\u003cp\u003epotassium voltage-gated channel subfamily Q member 2(KCNQ2) Homo sapiens The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250178990420,"sku":"ABM5031012-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250179023188,"sku":"ABM5031012-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/products\/reed-biotech-kcnq2-3-4-5-phospho-thr217-246-223-251-polyclonal-antibody-ra26618","provider":"ABMIUM","version":"1.0","type":"link"}