{"product_id":"reed-biotech-jmy-polyclonal-antibody-ra26558","title":"JMY Polyclonal Antibody","description":"\u003cp\u003efunction:Cofactor that increases p53\/TP53 response via its interaction with p300\/EP300. Increases p53\/TP53-dependent transcription and apoptosis, suggesting an important role in p53\/TP53 stress response such as DNA damage.,induction:By E2F.,PTM:Ubiquitinated by MDM2, leading to its subsequent degradation by the proteasome. In case of DNA damage, the interaction with MDM2 is altered, preventing degradation and allowing interaction with p300\/EP300 and its function in p53\/TP53 stress response.,similarity:Contains 1 WH2 domain.,subunit:Interacts with p300\/EP300, the complex being recruited to activated p53\/TP53. Interacts with TTC5.,\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57249955152212,"sku":"ABM5030952-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57249955184980,"sku":"ABM5030952-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/products\/reed-biotech-jmy-polyclonal-antibody-ra26558","provider":"ABMIUM","version":"1.0","type":"link"}