{"product_id":"reed-biotech-e2f-1-mouse-monoclonal-antibody-ra11111","title":"E2F-1 Mouse Monoclonal Antibody","description":"\u003cp\u003eE2F transcription factor 1(E2F1) Homo sapiens The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can media\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57249586708820,"sku":"ABM5041941-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57249586741588,"sku":"ABM5041941-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/products\/reed-biotech-e2f-1-mouse-monoclonal-antibody-ra11111","provider":"ABMIUM","version":"1.0","type":"link"}