{"product_id":"reed-biotech-dab2-rabbit-polyclonal-antibody-ra31915","title":"DAB2 Rabbit Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor\/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57251178152276,"sku":"ABM5036309-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57251178185044,"sku":"ABM5036309-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/products\/reed-biotech-dab2-rabbit-polyclonal-antibody-ra31915","provider":"ABMIUM","version":"1.0","type":"link"}