{"product_id":"reed-biotech-cd158a-polyclonal-antibody-ra22936","title":"CD158a Polyclonal Antibody","description":"\u003cp\u003ekiller cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1(KIR2DL1) Homo sapiens Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several \u0026amp;quot;framework\u0026amp;quot; genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250303705428,"sku":"ABM5027330-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250303738196,"sku":"ABM5027330-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/products\/reed-biotech-cd158a-polyclonal-antibody-ra22936","provider":"ABMIUM","version":"1.0","type":"link"}