{"product_id":"reed-biotech-cd148-polyclonal-antibody-ra22931","title":"CD148 Polyclonal Antibody","description":"\u003cp\u003eprotein tyrosine phosphatase, receptor type J(PTPRJ) Homo sapiens The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250277130580,"sku":"ABM5027325-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250277163348,"sku":"ABM5027325-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/products\/reed-biotech-cd148-polyclonal-antibody-ra22931","provider":"ABMIUM","version":"1.0","type":"link"}