{"product_id":"reed-biotech-blnk-polyclonal-antibody-ra22422","title":"BLNK Polyclonal Antibody","description":"\u003cp\u003eB-cell linker(BLNK) Homo sapiens This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250699051348,"sku":"ABM5026816-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250699084116,"sku":"ABM5026816-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/products\/reed-biotech-blnk-polyclonal-antibody-ra22422","provider":"ABMIUM","version":"1.0","type":"link"}