{"product_id":"reed-biotech-baf53-polyclonal-antibody-ra22300","title":"BAF53 Polyclonal Antibody","description":"\u003cp\u003eactin like 6A(ACTL6A) Homo sapiens This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1\/brm-associated factor) complex in mammals, which is functionally related to SWI\/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin\/matrix. Three transcript variants that encode two different protein\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250051555668,"sku":"ABM5026694-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250051588436,"sku":"ABM5026694-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/products\/reed-biotech-baf53-polyclonal-antibody-ra22300","provider":"ABMIUM","version":"1.0","type":"link"}