{"product_id":"reed-biotech-apaf-1-polyclonal-antibody-ra21954","title":"Apaf-1 Polyclonal Antibody","description":"\u003cp\u003eapoptotic peptidase activating factor 1(APAF1) Homo sapiens This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57249751433556,"sku":"ABM5026348-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57249751466324,"sku":"ABM5026348-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/products\/reed-biotech-apaf-1-polyclonal-antibody-ra21954","provider":"ABMIUM","version":"1.0","type":"link"}