{"product_id":"rabbit-polyclonal-antibody-to-trim11-p31255","title":"Anti-TRIM11 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eTRIM11\u003c\/strong\u003e is an E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX. TRIM11 mediates PAX6 ubiquitination leading to proteasomal degradation, thereby modulating cortical neurogenesis. TRIM11 may also inhibit PAX6 transcriptional activity, possibly in part by preventing the binding of PAX6 to its consensus sequences.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58031453569364,"sku":"ABM414461-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58031453602132,"sku":"ABM414461-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58031453634900,"sku":"ABM414461-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-trim11-p31255","provider":"ABMIUM","version":"1.0","type":"link"}