{"product_id":"rabbit-polyclonal-antibody-to-taz-phospho-ser89-p44038","title":"Anti-TAZ (phospho-Ser89) Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eWWTR1\u003c\/strong\u003e is a transcriptional coactivator which acts as a downstream regulatory target in the Hippo signalling pathway that plays a pivotal role in organ size control and tumour suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3\/MST2 and STK4\/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1\/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1\/TAZ. WWTR1 enhances PAX8 and NKX2-1\/TTF1-dependent gene activation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58167865442644,"sku":"ABM420735-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58167865475412,"sku":"ABM420735-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58167865508180,"sku":"ABM420735-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-taz-phospho-ser89-p44038","provider":"ABMIUM","version":"1.0","type":"link"}