{"product_id":"rabbit-polyclonal-antibody-to-srpk2-p10216","title":"Anti-SRPK2 Rabbit Polyclonal Antibody","description":"\u003cp\u003eSerine\/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine\/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. SRPK2 promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53\/TP53 phosphorylation thereby relieving the repressive effect of p53\/TP53 on cyclin-D1 (CCND1) expression.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58007077585236,"sku":"ABM405426-1","price":210.0,"currency_code":"USD","in_stock":true},{"title":"100 µL","offer_id":58007077618004,"sku":"ABM405426-2","price":300.0,"currency_code":"USD","in_stock":true},{"title":"1 mL","offer_id":58007077650772,"sku":"ABM405426-3","price":2237.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-srpk2-p10216","provider":"ABMIUM","version":"1.0","type":"link"}