{"product_id":"rabbit-polyclonal-antibody-to-scaf8-p33316","title":"Anti-SCAF8 Rabbit Polyclonal Antibody","description":"\u003cp\u003eAnti-terminator protein required to prevent early mRNA termination during transcription. Together with SCAF4, acts by suppressing the use of early, alternative poly(A) sites, thereby preventing the accumulation of non-functional truncated proteins. Mechanistically, associates with the phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit (POLR2A), and subsequently binds nascent RNA upstream of early polyadenylation sites to prevent premature mRNA transcript cleavage and polyadenylation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58157074809172,"sku":"ABM416218-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58157074841940,"sku":"ABM416218-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58157074874708,"sku":"ABM416218-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-scaf8-p33316","provider":"ABMIUM","version":"1.0","type":"link"}