{"product_id":"rabbit-polyclonal-antibody-to-rspo3-p33799","title":"Anti-RSPO3 Rabbit Polyclonal Antibody","description":"\u003cp\u003eActivator of the canonical Wnt signalling pathway by acting as a ligand for LGR4-6 receptors, which acts as a key regulator of angiogenesis. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signalling pathway to increase expression of target genes. Also regulates the canonical Wnt\/beta-catenin-dependent pathway and non-canonical Wnt signalling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signalling pathway.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58157159350612,"sku":"ABM416670-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58157159383380,"sku":"ABM416670-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58157159416148,"sku":"ABM416670-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-rspo3-p33799","provider":"ABMIUM","version":"1.0","type":"link"}