{"product_id":"rabbit-polyclonal-antibody-to-rpap2-p43708","title":"Anti-RPAP2 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eRPAP2\u003c\/strong\u003e is a protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. RPAP2 recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes. Downstream of EIF2AK3\/PERK, dephosphorylates ERN1, a sensor for the endoplasmic reticulum unfolded protein response (UPR), to abort failed ER-stress adaptation and trigger apoptosis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58167718445396,"sku":"ABM420570-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58167718478164,"sku":"ABM420570-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58167718510932,"sku":"ABM420570-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-rpap2-p43708","provider":"ABMIUM","version":"1.0","type":"link"}