{"product_id":"rabbit-polyclonal-antibody-to-rnf34-p31670","title":"Anti-RNF34 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eRNF34\u003c\/strong\u003e is an E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis. RNF34 may mediate 'Lys-48'-linked polyubiquitination of RIPK1 and its subsequent proteasomal degradation thereby indirectly regulating the tumour necrosis factor-mediated signalling pathway (Ref.13).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58035409125716,"sku":"ABM414842-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58035409158484,"sku":"ABM414842-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58035409191252,"sku":"ABM414842-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-rnf34-p31670","provider":"ABMIUM","version":"1.0","type":"link"}