{"product_id":"rabbit-polyclonal-antibody-to-rnf145-p34710","title":"Anti-RNF145 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eRNF145\u003c\/strong\u003e is an E3 ubiquitin ligase that catalyses the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. In response to bacterial infection, negatively regulates the phagocyte oxidative burst by controlling the turnover of the NADPH oxidase complex subunits. RNF145 promotes monoubiquitination of CYBA and 'Lys-48'-linked polyubiquitination and degradation of CYBB NADPH oxidase catalytic subunits, both essential for the generation of antimicrobial reactive oxygen species.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58161316331860,"sku":"ABM417475-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58161316364628,"sku":"ABM417475-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58161316397396,"sku":"ABM417475-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-rnf145-p34710","provider":"ABMIUM","version":"1.0","type":"link"}