{"product_id":"rabbit-polyclonal-antibody-to-rnf139-p33502","title":"Anti-RNF139 Rabbit Polyclonal Antibody","description":"\u003cp\u003eE3-ubiquitin ligase; acts as a negative regulator of cell proliferation through mechanisms involving G2\/M arrest and cell death. RNF139 is required for MHC class I ubiquitination in cells expressing the cytomegalovirus protein US2 before dislocation from the endoplasmic reticulum (ER). Affects SREBP processing by hindering the SREBP-SCAP complex translocation from the ER to the Golgi, thereby reducing SREBF2 target gene expression.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58157103972692,"sku":"ABM416386-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58157104005460,"sku":"ABM416386-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58157104038228,"sku":"ABM416386-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-rnf139-p33502","provider":"ABMIUM","version":"1.0","type":"link"}