{"product_id":"rabbit-polyclonal-antibody-to-psme4-n-term-p33804","title":"Anti-PSME4 (N-Term) Rabbit Polyclonal Antibody","description":"\u003cp\u003eAssociated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during spermatogenesis and DNA damage response. PSME4 recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. PSME4 binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58157159842132,"sku":"ABM416675-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58157159874900,"sku":"ABM416675-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58157159907668,"sku":"ABM416675-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-psme4-n-term-p33804","provider":"ABMIUM","version":"1.0","type":"link"}