{"product_id":"rabbit-polyclonal-antibody-to-phospho-atm-s1981-p30249","title":"Anti-Phospho-ATM(S1981) Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eATM\u003c\/strong\u003e is a serine\/threonine protein kinase which activates checkpoint signalling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. ATM recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58031236448596,"sku":"ABM413521-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58031236481364,"sku":"ABM413521-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58031236514132,"sku":"ABM413521-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-phospho-atm-s1981-p30249","provider":"ABMIUM","version":"1.0","type":"link"}