{"product_id":"rabbit-polyclonal-antibody-to-pcsk9-p32959","title":"Anti-PCSK9 Rabbit Polyclonal Antibody","description":"\u003cp\u003eCrucial player in the regulation of plasma cholesterol homeostasis. PCSK9 binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1\/APOER) and apolipoprotein receptor 2 (LRP8\/APOER2), and promotes their degradation in intracellular acidic compartments. PCSK9 acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1\/ARH-mediated pathway.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58156542034260,"sku":"ABM415917-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58156542067028,"sku":"ABM415917-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58156542099796,"sku":"ABM415917-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-pcsk9-p32959","provider":"ABMIUM","version":"1.0","type":"link"}