{"product_id":"rabbit-polyclonal-antibody-to-panopsin-p43616","title":"Anti-Panopsin Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eOPN3\u003c\/strong\u003e is a G protein-coupled photoreceptor that selectively activates G(i\/o) proteins in response to light, thereby decreasing intracellular cAMP levels. Activation occurs when the opsin-bound cis-retinal chromophore absorbs a photon and isomerizes to all-trans-retinal, inducing a conformational change in the opsin that triggers a G protein-mediated phototransduction cascade. OPN3 mediates blue light-induced pigmentation in melanocytes by activating calcium\/CAMK2 signalling, followed by phosphorylation of CREB, p38, ERK and MITF.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58167671390548,"sku":"ABM420480-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58167671423316,"sku":"ABM420480-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58167671456084,"sku":"ABM420480-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-panopsin-p43616","provider":"ABMIUM","version":"1.0","type":"link"}