{"product_id":"rabbit-polyclonal-antibody-to-opn4-p52116","title":"Anti-OPN4 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eOPN4\u003c\/strong\u003e is a G protein-coupled photoreceptor that signals through the G(q\/11) family of G proteins in response to light in intrinsically photosensitive retinal ganglion cells (ipRGCs). OPN4 can also activate other G proteins, including G(i\/o) and G(s), depending on the cell type, leading to either activation or inhibition of adenylate cyclase and cAMP-dependent signalling. Activation occurs when opsin-bound cis-retinal chromophore absorbs a photon and isomerizes to all-trans-retinal, inducing a conformational change in the opsin that triggers a G protein-mediated phototransduction cascade.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58168929026388,"sku":"ABM421187-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58168929059156,"sku":"ABM421187-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58168929091924,"sku":"ABM421187-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-opn4-p52116","provider":"ABMIUM","version":"1.0","type":"link"}