{"product_id":"rabbit-polyclonal-antibody-to-mmachc-p32357","title":"Anti-MMACHC Rabbit Polyclonal Antibody","description":"\u003cp\u003eCobalamin (vitamin B12) cytosolic chaperone that catalyses the reductive decyanation of cyanocob(III)alamin (cyanocobalamin, CNCbl) to yield cob(II)alamin and cyanide, using FAD or FMN as cofactors and NADPH as cosubstrate. Cyanocobalamin constitutes the inactive form of vitamin B12 introduced from the diet, and is converted into the active cofactors methylcobalamin (MeCbl) involved in methionine biosynthesis, and 5'-deoxyadenosylcobalamin (AdoCbl) involved in the TCA cycle. MMACHC forms a complex with the lysosomal transporter ABCD4 and its chaperone LMBRD1, to transport cobalamin across the lysosomal membrane into the cytosol.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58148264739156,"sku":"ABM415434-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58148264771924,"sku":"ABM415434-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58148264804692,"sku":"ABM415434-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-mmachc-p32357","provider":"ABMIUM","version":"1.0","type":"link"}