{"product_id":"rabbit-polyclonal-antibody-to-ksr-n-term-e174-p30173","title":"Anti-KSR (N-term E174) Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eKSR1\u003c\/strong\u003e forms part of a multiprotein signalling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases. Independently of its kinase activity, acts as MAP2K1\/MEK1 and MAP2K2\/MEK2-dependent allosteric activator of BRAF; upon binding to MAP2K1\/MEK1 or MAP2K2\/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1\/MEK1 and\/or MAP2K2\/MEK2. KSR1 promotes activation of MAPK1 and\/or MAPK3, both in response to EGF and to cAMP.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58031229862228,"sku":"ABM413470-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58031229894996,"sku":"ABM413470-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58031229927764,"sku":"ABM413470-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-ksr-n-term-e174-p30173","provider":"ABMIUM","version":"1.0","type":"link"}