{"product_id":"rabbit-polyclonal-antibody-to-irs2-p33869","title":"Anti-IRS2 Rabbit Polyclonal Antibody","description":"\u003cp\u003esignalling adapter protein that participates in the signal transduction from two prominent receptor tyrosine kinases, insulin receptor\/INSR and insulin-like growth factor I receptor\/IGF1R. IRS2 plays therefore an important role in development, growth, glucose homeostasis as well as lipid metabolism. Upon phosphorylation by the insulin receptor, functions as a signalling scaffold that propagates insulin action through binding to SH2 domain-containing proteins including the p85 regulatory subunit of PI3K, NCK1, NCK2, GRB2 or SHP2.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58157168263508,"sku":"ABM416733-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58157168296276,"sku":"ABM416733-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58157168329044,"sku":"ABM416733-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-irs2-p33869","provider":"ABMIUM","version":"1.0","type":"link"}