{"product_id":"rabbit-polyclonal-antibody-to-il-36-beta-p23281","title":"Anti-IL-36 beta Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eIL36B\u003c\/strong\u003e is a cytokine that binds to and signals through the IL1RL2\/IL-36R receptor which in turn activates NF-kappa-B and MAPK signalling pathways in target cells linked to a pro-inflammatory response. IL36B forms part of the IL-36 signalling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP. Stimulates production of interleukin-6 and interleukin-8 in synovial fibrobasts, articular chondrocytes and mature adipocytes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58024837906772,"sku":"ABM413004-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58024837939540,"sku":"ABM413004-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58024837972308,"sku":"ABM413004-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/enP232813.jpg?v=1793205450","url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-il-36-beta-p23281","provider":"ABMIUM","version":"1.0","type":"link"}