{"product_id":"rabbit-polyclonal-antibody-to-gsk3-beta-p23563","title":"Anti-GSK3 beta Rabbit Polyclonal Antibody","description":"\u003cp\u003eConstitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signalling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1\/beta-catenin, APC, AXIN1, DPYSL2\/CRMP2, JUN, NFATC1\/NFATC, MAPT\/TAU and MACF1. Requires primed phosphorylation of the majority of its substrates. In skeletal muscle, contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58031182872916,"sku":"ABM413255-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58031182905684,"sku":"ABM413255-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58031182938452,"sku":"ABM413255-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-gsk3-beta-p23563","provider":"ABMIUM","version":"1.0","type":"link"}