{"product_id":"rabbit-polyclonal-antibody-to-dkk2-p00334","title":"Anti-DKK2 Rabbit Polyclonal Antibody","description":"\u003cp\u003eAntagonizes canonical Wnt signalling by inhibiting LRP5\/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5\/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58006391554388,"sku":"ABM400983-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58006391587156,"sku":"ABM400983-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58006391619924,"sku":"ABM400983-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-dkk2-p00334","provider":"ABMIUM","version":"1.0","type":"link"}