{"product_id":"rabbit-polyclonal-antibody-to-cln3-p31261","title":"Anti-CLN3 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eCLN3\u003c\/strong\u003e mediates microtubule-dependent, anterograde transport connecting the Golgi network, endosomes, autophagosomes, lysosomes and plasma membrane, and participates in several cellular processes such as regulation of lysosomal pH, lysosome protein degradation, receptor-mediated endocytosis, autophagy, transport of proteins and lipids from the TGN, apoptosis and synaptic transmission. CLN3 facilitates the proteins transport from trans-Golgi network (TGN)-to other membrane compartments such as transport of microdomain-associated proteins to the plasma membrane, IGF2R transport to the lysosome where it regulates the CTSD release leading to regulation of CTSD maturation and thereby APP intracellular processing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58031454945620,"sku":"ABM414467-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58031454978388,"sku":"ABM414467-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58031455011156,"sku":"ABM414467-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-cln3-p31261","provider":"ABMIUM","version":"1.0","type":"link"}