{"product_id":"rabbit-polyclonal-antibody-to-caspase-1-phospho-ser376-p44564","title":"Anti-Caspase-1 (phospho Ser376) Rabbit Polyclonal Antibody","description":"\u003cp\u003eThiol protease involved in a variety of inflammatory processes by proteolytically cleaving other proteins, such as the precursors of the inflammatory cytokines interleukin-1 beta (IL1B) and interleukin 18 (IL18) as well as the pyroptosis inducer Gasdermin-D (GSDMD), into active mature peptides. CASP1 plays a key role in cell immunity as an inflammatory response initiator: once activated through formation of an inflammasome complex, it initiates a pro-inflammatory response through the cleavage of the two inflammatory cytokines IL1B and IL18, releasing the mature cytokines which are involved in a variety of inflammatory processes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58168785240404,"sku":"ABM421008-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58168785273172,"sku":"ABM421008-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58168785305940,"sku":"ABM421008-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/rabbit-polyclonal-antibody-to-caspase-1-phospho-ser376-p44564","provider":"ABMIUM","version":"1.0","type":"link"}