{"product_id":"proteogenix-rademikibart-biosimilar-anti-il-4ra-mab-research-grade","title":"Rademikibart Biosimilar – Anti-IL-4RA mAb – Research Grade","description":"\u003ch3\u003eRademikibart Biosimilar – Anti-IL-4RA mAb – Research Grade Introduction\u003c\/h3\u003e \u003cp\u003eRademikibart Biosimilar is a novel therapeutic antibody that targets the Interleukin-4 receptor alpha (IL-4RA) and is designed for research purposes. This biosimilar is a monoclonal antibody (mAb) that mimics the structure and function of the original antibody, making it an effective tool for studying the role of IL-4RA in various biological processes.\u003c\/p\u003e \u003ch3\u003eStructure of Rademikibart Biosimilar\u003c\/h3\u003e \u003cp\u003eRademikibart Biosimilar is a recombinant antibody that is produced in a laboratory using advanced biotechnology techniques. It is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. The heavy chains contain a constant region and a variable region, while the light chains only have a variable region. The variable regions are responsible for binding to the IL-4RA target, while the constant regions provide stability and effector functions.\u003c\/p\u003e \u003ch3\u003eActivity of Rademikibart Biosimilar\u003c\/h3\u003e \u003cp\u003eRademikibart Biosimilar specifically targets the IL-4RA, which is a cell surface receptor that is involved in the immune response. IL-4RA is expressed on a variety of immune cells, including T cells, B cells, and macrophages. When IL-4RA is activated by its ligand, interleukin-4 (IL-4), it triggers a signaling cascade that leads to the activation of these immune cells.\u003c\/p\u003e \u003cp\u003eBy binding to IL-4RA, Rademikibart Biosimilar blocks the interaction between IL-4 and its receptor, thereby inhibiting the downstream signaling and activation of immune cells. This activity makes it a valuable tool for studying the role of IL-4RA in various immune processes, such as allergic responses and autoimmune diseases.\u003c\/p\u003e \u003ch3\u003eApplication of Rademikibart Biosimilar\u003c\/h3\u003e \u003cp\u003eRademikibart Biosimilar is primarily used in research settings to study the function of IL-4RA. It can be used in in vitro experiments to investigate the effects of IL-4RA signaling on different cell types. Additionally, it can be used in animal studies to assess the role of IL-4RA in disease models.\u003c\/p\u003e \u003cp\u003eFurthermore, Rademikibart Biosimilar has potential therapeutic applications. IL-4RA is known to play a crucial role in allergic diseases, such as asthma and atopic dermatitis. By blocking IL-4RA, Rademikibart Biosimilar may have the potential to treat these conditions. Clinical trials are currently underway to evaluate the safety and efficacy of Rademikibart Biosimilar as a therapeutic antibody.\u003c\/p\u003e \u003ch3\u003eConclusion\u003c\/h3\u003e \u003cp\u003eIn summary, Rademikibart Biosimilar is a recombinant monoclonal antibody that targets the IL-4RA and is used for research purposes. Its unique structure and activity make it a valuable tool for studying the role of IL-4RA in immune processes. Additionally, it has potential therapeutic applications in treating allergic diseases. With ongoing research and clinical trials, Rademikibart Biosimilar has the potential to contribute to the advancement of scientific knowledge and the development of new treatments for immune-related disorders.\u003c\/p\u003e\u003cp\u003eProteoGenix catalogue number PX-TA1965. For research use only.\u003c\/p\u003e\u003cp\u003eTarget: Rademikibart Biosimilar – Anti-IL-4RA mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Buffer: 0.01M PBS, pH 7.4; Applications: ELISA, WB.\u003c\/p\u003e\u003cp\u003eAvailable configurations: 50ug, 100ug, 1mg.\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.proteogenix.science\/wp-content\/uploads\/documents\/Datasheets\/PX-TA1965.pdf\"\u003eDownload the manufacturer datasheet\u003c\/a\u003e\u003c\/p\u003e","brand":"ProteoGenix","offers":[{"title":"50ug","offer_id":57357669368148,"sku":"ABM134097-1","price":111.2,"currency_code":"GBP","in_stock":true},{"title":"100ug","offer_id":57357669400916,"sku":"ABM134097-2","price":164.0,"currency_code":"GBP","in_stock":true},{"title":"1mg","offer_id":57357669433684,"sku":"ABM134097-3","price":332.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/bioactivity-validation-1-rademikibart-biosimilar-anti-il-4ra-mab-research-grade_37c2a7b0-1468-4280-838a-92e56e2fa787.jpg?v=1790890891","url":"https:\/\/www.abmium.com\/products\/proteogenix-rademikibart-biosimilar-anti-il-4ra-mab-research-grade","provider":"ABMIUM","version":"1.0","type":"link"}