{"product_id":"proteogenix-anti-human-cd59-polyclonal-antibody","title":"Anti-Human CD59 Polyclonal Antibody","description":"\u003cp\u003eAnti-Human CD59 Polyclonal Antibody: A Versatile Tool for Immunology Research\u003c\/p\u003e \u003ch2\u003eIntroduction:\u003c\/h2\u003e \u003cp\u003eAnti-Human CD59 Polyclonal Antibody is a highly specific and reliable tool for immunology research. This polyclonal antibody is designed to target the CD59 protein, also known as protectin, which is a cell surface glycoprotein involved in the regulation of complement-mediated cell lysis. With its wide range of applications and proven experimental use cases, this antibody is a valuable addition to any biotech laboratory.\u003c\/p\u003e \u003ch2\u003eBiological Function:\u003c\/h2\u003e \u003cp\u003eCD59 is a key regulator of the complement system, a crucial part of the immune response that helps defend the body against pathogens. This protein works by inhibiting the formation of the membrane attack complex (MAC), a structure that can cause cell lysis. By binding to CD59, this antibody can block the action of the MAC and prevent cell damage, making it an important tool for studying the immune response.\u003c\/p\u003e \u003ch2\u003eMain Applications:\u003c\/h2\u003e \u003cp\u003eThe Anti-Human CD59 Polyclonal Antibody has a wide range of applications in immunology research. It can be used in various techniques such as flow cytometry, immunohistochemistry, and Western blotting to detect and quantify CD59 expression in different cell types and tissues. This antibody is also suitable for functional studies, as it can inhibit the activity of CD59 and study its role in the complement system.\u003c\/p\u003e \u003ch2\u003eExperimental Use Cases:\u003c\/h2\u003e \u003cp\u003eThis polyclonal antibody has been extensively used in research on various diseases, including autoimmune disorders, infectious diseases, and cancer. In a study published in the Journal of Immunology, researchers used this antibody to investigate the role of CD59 in autoimmune kidney disease. Another study published in the Journal of Virology used this antibody to study the role of CD59 in HIV infection. These examples demonstrate the versatility and reliability of this antibody in different research areas.\u003c\/p\u003e \u003cp\u003eThis polyclonal antibody is specifically designed for research use and is not intended for diagnostic or therapeutic purposes. It is produced in a host animal and purified using advanced techniques to ensure high specificity and sensitivity. With its high affinity and low background, this antibody is an ideal choice for studying CD59 in various research applications.\u003c\/p\u003e\u003cp\u003eProteoGenix catalogue number ARO-A22048. For research use only.\u003c\/p\u003e\u003cp\u003eTarget: CD59 glycoprotein; 1F5 antigen; 20 kDa homologous restriction factor; HRF-20; HRF20; MAC-inhibitory protein; MAC-IP; MEM43 antigen; Membrane attack complex inhibition factor; MACIF; Membrane inhibitor of reactive lysis; MIRL; Protectin; CD59; CD59; MIC11; MIN1; MIN2; MIN3; MSK21; Clonality: Polyclonal Antibody; Reactivity: Human; Applications: ELISA, IHC.\u003c\/p\u003e\u003cp\u003eAvailable configurations: 50ug, 100ug, 1mg.\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.proteogenix.science\/wp-content\/uploads\/documents\/Datasheets\/ARO-A22048.pdf\"\u003eDownload the manufacturer datasheet\u003c\/a\u003e\u003c\/p\u003e","brand":"ProteoGenix","offers":[{"title":"50ug","offer_id":57353762537812,"sku":"ABM121718-1","price":159.2,"currency_code":"GBP","in_stock":true},{"title":"100ug","offer_id":57353762570580,"sku":"ABM121718-2","price":231.2,"currency_code":"GBP","in_stock":true},{"title":"1mg","offer_id":57353762603348,"sku":"ABM121718-3","price":679.2,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Primaryantibodies-CCt9H6Tc_aeeb3479-cd70-4697-badc-475a97538ee2.svg?v=1790886061","url":"https:\/\/www.abmium.com\/products\/proteogenix-anti-human-cd59-polyclonal-antibody","provider":"ABMIUM","version":"1.0","type":"link"}