{"product_id":"proteogenix-anti-digoxigenin-antibody-19a11","title":"Anti-Digoxigenin Antibody (19A11)","description":"\u003ch2\u003eIntroduction\u003c\/h2\u003e \u003cp\u003eAnti-Digoxigenin Antibody (19A11) is a monoclonal antibody that specifically recognizes the hapten digoxigenin (DIG). It is widely used in various research applications and has potential therapeutic applications as well. In this article, we will discuss the structure, activity, and potential applications of Anti-Digoxigenin Antibody (19A11).\u003c\/p\u003e \u003ch2\u003eStructure of Anti-Digoxigenin Antibody (19A11)\u003c\/h2\u003e \u003cp\u003eAnti-Digoxigenin Antibody (19A11) is a monoclonal antibody, meaning it is produced by a single type of immune cell and is highly specific to its target antigen, digoxigenin. It is composed of two heavy chains and two light chains, each with a unique amino acid sequence. The variable regions of the antibody, also known as the antigen-binding sites, are responsible for recognizing and binding to digoxigenin.\u003c\/p\u003e \u003cp\u003eThe constant region of the antibody, on the other hand, is responsible for immune effector functions such as complement activation and binding to Fc receptors on immune cells. The constant region of Anti-Digoxigenin Antibody (19A11) belongs to the IgG subclass and is therefore able to activate complement and bind to Fc receptors, making it useful for various research and therapeutic applications.\u003c\/p\u003e \u003ch2\u003eActivity of Anti-Digoxigenin Antibody (19A11)\u003c\/h2\u003e \u003cp\u003eAnti-Digoxigenin Antibody (19A11) is highly specific for digoxigenin and has a high affinity for its target antigen. This means that it can bind to digoxigenin with great precision and strength, making it a valuable tool for detecting and quantifying digoxigenin in various samples.\u003c\/p\u003e \u003cp\u003eOne of the main activities of Anti-Digoxigenin Antibody (19A11) is its ability to detect digoxigenin in various assays, such as enzyme-linked immunosorbent assays (ELISA) and immunohistochemistry. In these assays, the antibody is used to capture and detect digoxigenin, allowing for the quantification and localization of the hapten in different samples.\u003c\/p\u003e \u003cp\u003eAnother important activity of Anti-Digoxigenin Antibody (19A11) is its ability to neutralize the effects of digoxin, a cardiac glycoside that is commonly used in the treatment of heart failure. Digoxin and digoxigenin have similar structures, and Anti-Digoxigenin Antibody (19A11) can bind to and neutralize digoxin, making it a potential therapeutic agent for the treatment of digoxin overdose or toxicity.\u003c\/p\u003e \u003ch2\u003eApplications of Anti-Digoxigenin Antibody (19A11)\u003c\/h2\u003e \u003cp\u003eAnti-Digoxigenin Antibody (19A11) has a wide range of applications in both research and potential therapeutic settings. Some of the key applications of this antibody include:\u003c\/p\u003e \u003ch2\u003eResearch use\u003c\/h2\u003e \u003cp\u003eAs mentioned earlier, Anti-Digoxigenin Antibody (19A11) is commonly used in various research applications, such as ELISA and immunohistochemistry, to detect and quantify digoxigenin. It is also used in Western blotting, flow cytometry, and immunofluorescence assays to study the expression and localization of digoxigenin in different samples.\u003c\/p\u003e \u003cp\u003eIn addition, Anti-Digoxigenin Antibody (19A11) can be used in studies involving the neutralization of digoxin, such as in the investigation of digoxin toxicity or the development of antidotes for digoxin overdose.\u003c\/p\u003e \u003ch2\u003eTherapeutic target\u003c\/h2\u003e \u003cp\u003eThe ability of Anti-Digoxigenin Antibody (19A11) to neutralize the effects of digoxin makes it a potential therapeutic target for the treatment of digoxin overdose or toxicity. This antibody can be used in combination with other therapies to reduce the harmful effects of digoxin and improve patient outcomes.\u003c\/p\u003e\u003cp\u003eProteoGenix catalogue number ARO-A14651. For research use only.\u003c\/p\u003e\u003cp\u003eTarget: Anti-General Monoclonal Antibody; Host: Human; Clonality: Monoclonal Antibody; Reactivity: Anti-General Monoclonal Antibody, General; Applications: ELISA.\u003c\/p\u003e\u003cp\u003eAvailable configurations: 50ug, 100ug, 1mg.\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.proteogenix.science\/wp-content\/uploads\/documents\/Datasheets\/ARO-A14651.pdf\"\u003eDownload the manufacturer datasheet\u003c\/a\u003e\u003c\/p\u003e","brand":"ProteoGenix","offers":[{"title":"50ug","offer_id":57356298158420,"sku":"ABM130881-1","price":196.0,"currency_code":"GBP","in_stock":true},{"title":"100ug","offer_id":57356298191188,"sku":"ABM130881-2","price":287.2,"currency_code":"GBP","in_stock":true},{"title":"1mg","offer_id":57356298223956,"sku":"ABM130881-3","price":892.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/sds-validation-1-anti-digoxigenin-antibody-19a11_9ff69e8f-2147-43a1-8f50-d1100b03ee5e.jpg?v=1791496325","url":"https:\/\/www.abmium.com\/products\/proteogenix-anti-digoxigenin-antibody-19a11","provider":"ABMIUM","version":"1.0","type":"link"}