{"product_id":"proteogenix-anti-dbt-polyclonal-antibody","title":"Anti-DBT Polyclonal Antibody","description":"\u003cp\u003eAnti-DBT Polyclonal Antibody\u003c\/p\u003e \u003ch2\u003eBiological Function:\u003c\/h2\u003e \u003cp\u003eAnti-DBT Polyclonal Antibody is a high-quality antibody that specifically targets the dihydroxyacetone phosphate acyltransferase (DBT) protein. DBT is an essential enzyme involved in the breakdown of amino acids, specifically the branched-chain amino acids (BCAAs) leucine, isoleucine, and valine. This antibody binds to DBT and inhibits its activity, leading to a decrease in BCAA metabolism.\u003c\/p\u003e \u003ch2\u003eMain Applications:\u003c\/h2\u003e \u003cp\u003eThis antibody is primarily used in research studies to investigate the role of DBT in various biological processes. It has been shown to be effective in studying BCAA metabolism, as well as its involvement in diseases such as maple syrup urine disease and liver cirrhosis. Additionally, this antibody can be used in diagnostic assays to detect changes in DBT levels, providing valuable insights into metabolic disorders.\u003c\/p\u003e \u003ch2\u003eExperimental Use Cases:\u003c\/h2\u003e \u003cp\u003eAnti-DBT Polyclonal Antibody has been successfully used in various experimental settings. In one study, it was used to investigate the effects of DBT inhibition on cancer cell growth and survival. The results showed that blocking DBT activity with this antibody led to a significant decrease in cancer cell proliferation. In another study, this antibody was used to explore the role of DBT in muscle metabolism and its potential as a therapeutic target for muscle-wasting diseases.\u003c\/p\u003e \u003cp\u003eWith its high specificity and sensitivity, this antibody has also been used in immunohistochemistry and Western blotting techniques to detect DBT expression in tissue samples. These experiments have provided valuable insights into the localization and expression patterns of DBT in different tissues and organs.\u003c\/p\u003e \u003cp\u003eIn summary, Anti-DBT Polyclonal Antibody is a valuable tool for researchers studying BCAA metabolism and its implications in various diseases. Its versatility and reliability make it a crucial component in the investigation of DBT function and its potential as a therapeutic target. Choose this antibody for accurate and reproducible results in your experiments.\u003c\/p\u003e \u003cp\u003eKeywords: Anti-DBT Polyclonal Antibody, dihydroxyacetone phosphate acyltransferase, BCAAs, metabolic disorders, cancer cell growth, muscle metabolism, immunohistochemistry, Western blotting, therapeutic target, research studies.\u003c\/p\u003e\u003cp\u003eProteoGenix catalogue number ARO-A22079. For research use only.\u003c\/p\u003e\u003cp\u003eTarget: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial; 2.3.1.168; 52 kDa mitochondrial autoantigen of primary biliary cirrhosis; Branched chain 2-oxo-acid dehydrogenase complex component E2; BCOADC-E2; Branched-chain alpha-keto acid dehydrogenase complex component E2; BCKAD-E2; BCKADE2; BCKDH-E2; Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex; Dihydrolipoamide branched chain transacylase; Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; DBT; BCATE2; BCKDHE2; Clonality: Polyclonal Antibody; Applications: ELISA, IHC.\u003c\/p\u003e\u003cp\u003eAvailable configurations: 50ug, 100ug, 1mg.\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.proteogenix.science\/wp-content\/uploads\/documents\/Datasheets\/ARO-A22079.pdf\"\u003eDownload the manufacturer datasheet\u003c\/a\u003e\u003c\/p\u003e","brand":"ProteoGenix","offers":[{"title":"50ug","offer_id":57353746252116,"sku":"ABM121688-1","price":151.2,"currency_code":"GBP","in_stock":true},{"title":"100ug","offer_id":57353746284884,"sku":"ABM121688-2","price":204.0,"currency_code":"GBP","in_stock":true},{"title":"1mg","offer_id":57353746317652,"sku":"ABM121688-3","price":695.2,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Primaryantibodies-CCt9H6Tc_af3a6235-8b6c-498c-87e7-70b8477731b4.svg?v=1790886038","url":"https:\/\/www.abmium.com\/products\/proteogenix-anti-dbt-polyclonal-antibody","provider":"ABMIUM","version":"1.0","type":"link"}